General description

CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation.Endothelial cells also express this marker; therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms.^1-3Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells.⁴Staining of nonvascular tumors (excluding hematopoietic neoplasms) has not been observed.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

CD31 Positive Control Slides, Product No. 131S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide.

Preparation Note

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Quality